Обучение по природни науки и върхови технологии

Година XXIV, Книжка 6, 2015Следващ бройАрхивПредишен брой

Юбилей: 90 години на Катедрата по физикохимия на Софийския университет

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КАТЕДРАТА ПО ФИЗИКОХИМИЯ – АКЦЕНТИ ОТ МИНАЛОТО И ПЕРСПЕКТИВИ ЗА РАЗВИТИЕ В БЪДЕЩЕТО

Б. В. Тошев

Някои подробности от изследванията по термодинамика на капилярните системи, проведени в Катедрата по физикохимия на Софийския университет „Св. Климент Охридски“ през годините 1970 – 1990, са представени в настоящата статия. Втората част на статията прави анал...

Department of Physical Chemistry, University of Sofia, surface thermodynamics, capillarity, post-normal science

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HARD SPHERES MODEL OF THE ATOM

Roumen Tsekov

The finite size effect of electron and nucleus is accounted for in the model of atom. Due to their hard sphere repulsion the energy of the 1s orbital decreases and the corrections amount up to \(8 \%\) in Uranium. Several models for boundary conditions on t...

atom model, hard spheres, nuclei boundary conditions

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COMPLEX SYSTEMS FOR DRUG TRANSPORT ACROSS CELL MEMBRANES

Nikoleta Ivanova, Yana Tsoneva, Nina Ilkova, Anela Ivanova

Targeted drug delivery to specific tissues or cell compartments in the human organism is an advantageous route to overcoming multidrug resistance or reducing undesired side effects of pharmaceutics. Efficient specific targeting requires associating the drug wi...

drug delivery systems, anthracycline antibiotics, doxorubicin, cellpenetrating peptides, nanoparticles, biodegradable polymers

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SURFACE FUNCTIONALIZATION OF SILICA SOL-GEL MICROPARTICLES WITH EUROPIUM COMPLEXES

Nina Danchova, Gulay Ahmed, Michael Bredol, Stoyan Gutzov

The present contribution is focused on the relation preparation – structure – optical properties of hybrid silica powders containing Eu(III) complexes: \(\mathrm{SiO}_{2}\) : \(\left[\mathrm{Eu}(\mathrm{ntac})_{3}\right][\mathrm{pphendcn}]\) and \(\mathrm{Si...

silica, europium complexes, luminescence, sol-gel

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STUDY OF PROTEIN MODIFIED GOLD NANOPARTICLES IN BULK PHASE AND AT AIR/WATER INTERFACE

A. Chanachev, P. Georgiev, Tz. Ivanova, K. Balashev

The colorimetric assay based on the surface plasmon resonance of metal nanoparticles receives significant attention because of its simplicity, sensitivity and low cost. The preparation of stable suspensions of gold nanoparticles (GNPs) modified with proteins...

gold nanoparticles (GNPs), atomic force microscopy (AFM), transmission electron microscopy (TEM), bovine serum albumin (BSA), protein modified nanoparticles

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PARALLEL STABILITY ANALYSIS OF MEMBRANE LAMELLAR STRICTURES AND FOAM FILMS

Nikoleta G. Ivanova, Roumen Tsekov

In the frames of the DLVO theory the root mean square amplitude of capillary waves in a thin liquid film is calculated and its dependence on some important physical parameters is unveiled. Two important models are considered: films with classical interfaces a...

thin liquid films, lamellar structures, thickness fluctuations

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INTERFACIAL REORGANIZATION OF MOLECULAR ASSEMBLIES USED AS DRUG DELIVERY SYSTEMS

I. Panaiotov, Tz. Ivanova, K. Balashev, N. Grozev, I. Minkov, K. Mircheva

The number of potential applications of nanosized molecular assemblies such as vesicles, nanocapsules, biodegradable polyester matrix and more complex structures in drug research and nanomedicine is rapidly increasing with the developed technologies to tune...

vesicles, lipid nanocapsules, lung surfactants, spreading, model membrane monolayer

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ANOMALOUS DRAINAGE OF NANOFILMS FROM CONCENTRATED NACL SOLUTIONS OF TETRAETHYLENE GLYCOL OCTYL ETHER (C8E4)

Stoyan I. Karakashev

The drainage of planar foam nanofilms, stabilized by tetraethylene glycol octyl ether \(\left(\mathrm{C}_{8} \mathrm{E}_{4}\right)\) in aqueous solutions of NaCl was studied. The experiments on foam nanofilm drainage were performed at three different NaCl co...

nanofilms, foam film drainage, thin liquid films, salt solutions, non-ionic surfactants

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KINETICS OF THE OSMOTIC PROCESS AND THE POLARIZATION EFFECT

Boryan P. Radoev, Ivan L. Minkov, Emil D. Manev

Osmosis, i.e. the transport of fluids through a semipermeable membrane, has been investigated for more than a century, using open and closed osmotic devices. We have developed now a novel operative experimental approach, based on a controlled volume variat...

osmotic pressure, osmotic kinetics, concentration polarization

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WETTING BEHAVIOR OF A NATURAL AND A SYNTHETIC THERAPEUTIC PULMONARY SURFACTANTS

Lidia Alexandrova, Michail Nedyalkov, Dimo Platikanov

The wetting properties of aqueous solutions of two therapeutic pulmonary surfactants (TPS) with respect to solid surfaces with different degree of hydrophobicity \(\theta_{\mathrm{w}}\) have been studied. A special procedure for hydrophobization of the \(\ma...

pulmonary surfactant, therapeutic surfactant preparation, wetting behavior, contact angle, wetting liquid film